Education:
Bachelor of Science in Biochemistry, School of Biological Science and Technology, Shanxi University (1996-2000);
Doctor of Biochemistry and Molecular Biology, Institute of Biotechnology, Shanxi University (2000-2005);
Assistant Research Fellow, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (2005-2008);
Postdoctoral Fellow, Department of Chemistry and Biochemistry, University of Maryland, USA (2008-2010);
Associate Professor, Department of Chemical Biochemistry, School of Chemistry and Chemical Engineering, Xiamen University (2010-)

Principal Research Interests:
Studies on the Structure and Function of Proteins and Polypeptides

Selected Recent Publications:

1.T.Sun, Z.Wu, M.Luo, D.Lin, C.Guo*,Pranlukast, a novel binding ligand of human Raf1 kinase inhibitory protein.BiotechnolLett.38(8):1375-80 (2016).

2.H.Chen, H.Wang, T.Sun, S.Tian, D.Lin, C.Guo*, Recombinant preparation and functional studies of EspI ATP binding domain from Mycobacterium tuberculosis.Protein ExprPurif. 23:51-9 (2016).

3. K.Lin, Z.Yu, Y.Yu, X.Liao, P.Huang, C.Guo*, D.Lin*, Distinct effects of Cu2+-binding on oligomerization of human and rabbit prion proteins.ActaBiochimBiophys Sin (Shanghai). 47(10):842-50 (2015).

4. S.Tian, H. Chen, T. Sun, H. Wang, X. Zhang, Y. Liu, J. Xia, C.Guo*, D. Lin*, Expression, purification and characterization of Esx-1 secretion-associated protein EspL from Mycobacterium tuberculosis.Protein ExprPurif. 128:42-51 (2016).

5.Z.Wu, C.Fu, L.Shi, L.Ruan, D.Lin, C.Guo*, Structural basis for RKIP binding with its substrate Raf1 kinase.BiotechnolLett. 36(9):1869-74 (2014).

6. C. Guo*, C. Yi, Y. Peng, Y. Wen, D. Lin*, Solution structure and backbone dynamics ofhuman Raf-1 kinase inhibitor protein, BiochemBioph Res Co, 438(1): 129-32 (2013).

7. C. Fu, Y. Peng, X. Liao, C. Guo*, D. Lin*, (1)H, (13)C, (15)N backbone and side-chainresonance assignments of the human adenylate kinase 1 in apo form, Biomol NMR Assign,7(2): 155-8 (2013).

8. C. Guo*, R.Godoy-Ruiz, V.Tugarinov, High resolution measurement of methyl 13C(m)-13C and 1H(m)-13C(m) residual dipolar couplings in large proteins. J. Am. Chem. Soc. 132:13984 (2010).

9. C.Guo*, Y. Lian, Q, Liu, J. Liu, Y. Zhang, D. Lin, Soluble expression and characterization of a mouse epididymis- specific protein lipocalin6, Protein Expr. Puri, 69: 64 (2010)

10.C. Guo*, V. Tugarinov, Selective 1H-13C NMR spectroscopy of methyl groups in residually protonated samples of large proteins, J. Biomol. NMR, 46:127 (2010).

11.C. Guo*, C. Geng, V. Tugarinov,Selective backbone labeling of proteins using 1,2-13C2 -pyruvate as carbon source, J. Biomol. NMR. 44: 167(2009).

12.C. Guo*, H. Diao, Y. Lian, H. Yu, H. Gao, Y. Zhang, D. Lin, Recombinant expression and characterization of an epididymis-specific antimicrobial peptide BIN1b / SPAG11E, J. Biotechnol., 139: 33 (2009)

13.C. Guo*, D. Zhang, V. Tugarinov, A NMR experiment for simultaneous TROSY - based detection of amide and methyl groups in large proteins, J. Am. Chem. Soc. 130: 10872 (2008)

14.C. Guo*, V. Tugarinov, Identification of HN-Methyl NOEs in large proteins using simultaneous amide-methyl TROSY-based Detection, J. Biomol. NMR, 43: 21 (2008)