Education:

B.S., Xiamen University

Ph.D., Xiamen University

Principle Research Interests:

Directed Molecular Evolution

Micro-nano Interface Assembly and Recognition Mechanism

Microfluidic Techniques and Analysis

Liquid Biopsy

Single-cell Analysis

Selected Recent Publications:

1. Jialu Zhang, Bingqian Lin, Lingling Wu, Mengjiao Huang, Xingrui Li, Huimin Zhang, Jia Song, Wei Wang, Gang Zhao,* Yanling Song,* and Chaoyong Yang*, DNA Nanolithography Enables Highly Ordered Recognition Interface in Microfluidic Chip for Efficient Capture and Release of Circulating Tumor Cells, Angew. Chem. Int. Ed. 2020, DOI: 10.1002/anie.202005974

2. Huang, M; Yang, J; Wang, T; Song, J; Xia, J; Wu, L; Wang, W; Wu, Q; Zhu, Z; Song, Y*, Yang, C*. Homogeneous, Low-volume, Efficient and Sensitive Quantitation of Circulating Exosomal PD-L1 for Cancer Diagnosis and Immunotherapy Response Prediction. Angewandte Chemie International Edition 2019, DOI: 10.1002/ange.201916039

3. Song, J; Zheng, Y; Huang, M; Wu, L; Wang, W; Zhu, Z; Song, Y* and Yang, C. A Sequential Multi-dimensional Analysis Algorithm for Aptamer Identification based on Structure Analysis and Machine Learning. Analytical Chemistry 2019, DOI: 10.1021/acs.analchem.9b05203

4. Song, Y; Shi, Y; Huang, M; Wang, W; Wang, Y; Cheng, J; Lei, Z; Zhu, Z and Yang, C*. Bioinspired Engineering of a Multivalent Aptamer-Functionalized Nanointerface to Enhance the Capture and Release of Circulating Tumor Cells. Angewandte Chemie International Edition 2019, 58 (8), 2236 (Inside Cover)

5. Huang, M; Song, J; Huang, P; Chen, X; Wang, W; Zhu, Z; Song, Y* and Yang, C*. Molecular Crowding Evolution for Enabling Discovery of Enthalpy-Driven Aptamers for Robust Biomedical Applications. Analytical Chemistry 2019, 91 (16), 10879

6. Lin, B ^#; An, Y^#; Meng, L; Zhang, H; Song, J; Zhu, Z; Wen Liu*; Song, Y* and Yang, C*. Control of CRISPR-Cas9 with Small Molecule-activated Allosteric Aptamer Regulating sgRNAs. Chemical Communications 2019, 55 (81), 12223

7. Song, Y; Lin, B; Tian, T; Xu, X; Wang, W; Ruan, Q; Guo, J; Zhu, Z and Yang, C.* Recent Progress in Microfluidics-Based Biosensing. Analytical Chemistry 2019, 91 (1), 388

8. Gao, M; Guo, J; Song, Y*; Zhu, Z* and Yang, C*. Detection of T4 Polynucleotide Kinase via Allosteric Aptamer Probe Platform, ACS Applied Materials Interfaces 2017, 9 (44), 38356

9. Song, Y; Tian, T; Shi, Y; Liu, W; Zou, Y, Khajavand, T; Zhu, Z and Yang, C*. Enrichment and Single-Cell Analysis of Circulating Tumor Cells, Chemical Science 2017, 8 (3),1736

10. Tian, T; An, Y; Wu, Y; Song, Y*; Zhu, Z and Yang, C*. Integrated Distance-Based Origami Paper Analytical Device for One-Step Visualized Analysis, ACS Applied Materials Interfaces 2017, 9 (36), 30480

11. Song, Y; An, Y; Liu, W; Hou, W; Li, X; Lin B; Zhu, Z; Ge, S*; Yang, H* and Yang, C*. Centrifugal Micropipette-tip with Pressure Signal Readout for Portable Quantitative Detection of Myoglobin, Chemical Communications 2017, 53 (86), 11774